IAVI Report 11 (5), September 2007 - December 2007
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A STEP back?
Additional data released from the STEP trial raises questions about whether the vaccine may have increased the risk of HIV infection
'Stopping a steam train'
Immunizations and enrollment in a second trial with MRKAd5 have now been permanently stopped, and volunteers in the Phambili and STEP trials are being unblinded
Getting it right early
The STEP trial offers lessons for future preclinical/clinical AIDS vaccine development
Conference Coverage - Giving it their best shot
Researchers from many areas of vaccine development gathered recently to discuss the challenges of developing and delivering life-saving vaccines
What next?
As data analysis proceeds on the STEP trial, some future trials are placed in a temporary holding pattern