Vol. 12, No. 6, Nov.-Dec. 2008

Editor's Letter, HIV Transmission: The Genetic Bottleneck, Mucosal Vaccines: Insights from Different Fields, PrEP Work, Research Briefs

HIV Transmission: The Genetic Bottleneck

Researchers are finally getting a handle on the nature of the virus that is transmitted and establishes infection, offering promising hints for AIDS vaccine development



Vol. 12, No. 6 - Nov.-Dec. 2008Cover Art

One of the major themes in the recently held US presidential election was change. President-elect Barack Obama declared, “Change is coming to America.” Meanwhile, here at IAVI Report, we’ve been working on some changes of our own. And with this issue, we are very pleased to introduce readers to our newly designed publication. As you read through this issue you will find several new graphic and design elements meant to enhance the look of IAVI Report. We are especially excited to be printing full-page cover images, kindly provided by researchers to showcase their work. Over the coming months, more changes are on the way. Early next year we will launch an improved version of the iavireport.org website with additional features not available in the print publication. And for the first time, IAVI Report will also be available as an e-newsletter, so if you prefer to receive the publication by email, please just let us know.

These changes are based largely on feedback we received from the IAVI Report reader survey, and I would again like to thank everyone who took the time to provide their opinions and ideas about how to improve this publication.

Our primary goal, as always, is to provide up-to-date, accurate, engaging, and comprehensive coverage of AIDS vaccine research and development. In the future you can expect even more emphasis on the latest research trends, as well as the themes emerging from scientific conferences and meetings. It has been an interesting year in AIDS vaccine research—change is not only on the march in politics—and as the field moves ahead, the IAVI Report team will continue to track shifting research priorities, chronicle advances, and bring these stories to our readers.

—Kristen Jill Kresge, Managing Editor

Mucosal Vaccines: Insights from Different Fields

Researchers are joining forces to understand mucosal immunity and develop mucosal vaccines


PrEP Work

If effective, pre-exposure prophylaxis for HIV will offer many opportunities, but also numerous challenges


Research Briefs

Prime-Boost Regimen with Ad26 Offers Renewed Hope for T-cell Vaccines