IAVI Report Online Special Features
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AIDS Vaccine Trials 2006: Year In Review Last year 13 new trials of preventive AIDS vaccine candidates started in 8 countries around the world. All were either Phase I or Phase I/II trials designed to evaluate the safety and immunogenicity of the candidate vaccines. The Russian Federation began its first AIDS vaccine trial and three countries in sub-Saharan Africa—Kenya, Uganda, and Tanzania—initiated new trials. The map on the inside pages of this issue focuses on these trials as well as countries that started trials in 2003-2005 that are still ongoing. The accompanying table provides information on all ongoing preventive AIDS vaccine trials. For more information, visit the Database of AIDS Vaccine Trials. Please email any additions, comments, or updates to iavireport@iavi.org. English [PDF, 5.54 MB] Last updated: January 2007 |
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January 2007 VAX Special Issue: 2006 Year in Review English [PDF, 687 KB] Last updated: January 2007 |
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Deciphering
AIDS Vaccines The articles in this anthology have been carefully selected to include information regarding all aspects of the AIDS vaccine field and to help the reader understand more about the science of AIDS vaccines and the clinical trials process, as well as alternate HIV prevention strategies and other vaccines that may provide lessons for the AIDS vaccine field. English [PDF, 2.1 MB] Published: November 2006 |
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AIDS Vaccine Trials 2005: Year In Review In 2005, 13 new trials of preventive AIDS vaccine candidates began in 9 countries around the world. Two of these involved vaccine candidates that entered Phase II trials, an intermediate stage of clinical evaluation. India, China, and Rwanda started their first AIDS vaccine trials last year and South Africa began the country's first Phase II AIDS vaccine trial. Several of these newly initiated trials involved novel vaccination strategies, including prime-boost regimens where two candidates are administered separately to try to improve the immune responses induced. English [PDF, 3.0 MB] Last updated: January 2006 |
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IAVI database of AIDS vaccines in human trials The database includes preventive vaccines only—those intended for individuals who are not infected with HIV, for the purpose of preventing HIV infection or disease. Trials evaluating therapeutic effects of HIV vaccines in already infected people are not included here. Last updated: September 27, 2007 |
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AIDS Vaccine Trials 2004: Year In Review In 2004, fifteen new trials to test AIDS vaccine candidates were initiated in seven different countries. The most advanced of the newly-launched trials is a Phase IIb study, which is a proof of concept trial to see if this type of vaccine is effective in preventing infection with HIV. Eleven new Phase I trials, the first stage of testing vaccine candidates in humans, also began in 2004. The world map inside this special issue of VAX highlights the trials that began in 2004 and, along with the table below, provides a rundown of all the ongoing clinical trials of preventive AIDS vaccines around the world. English [PDF, 1.8 MB] Last updated: February 2005 |
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AIDS Vaccine Trials 2003: Year In Review These clinical trials of preventive AIDS vaccines began immunizations in 2003. Additional countries and sites will be added to some of these trials in 2004. For a complete list of all preventive HIV vaccine trials, see the IAVI database of AIDS vaccines in human trials. English [PDF, 534 KB] Last updated: January 2004 |
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Global distribution of HIV-1 subtypes and recombinants This map summarizes current understanding of the global distribution of HIV-1 strains. English [PDF, 687 KB] Last updated: August 2003 |
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Working together: The global search for an AIDS vaccine An anthology of IAVI Report articles on the progress and challenges facing AIDS vaccine development. English [PDF 295 KB] Last updated: July 2002 |